If you are using R5, you should use the Administration  
Client to set fields in server configuration. Select the  
Configuration Tab of the Administration client and then go  
to Configurations. Select or create the configuration  
document for your MTA server. Select the Router/SMTP tab of  
the configuration document. Then choose Restrictions and  
Controls, then SMTP Inbound controls.  
In the field "Allow messages from external Internet domains  
to be sent only to the following Internet domains" enter the  
name of the domain your POP3 clients use  (e.g. nhc.com).  
Save the document. There are additional fields that you can  
configure to allow specific domains to relay messages, but  
these get a little confusing. For complete details, see the  
document "Restricting who can use your system to relay  
Internet mail"  
(http://doc.notes.net/domino_notes/5.0.3/help5_admin.nsf/078c27b23262ffff852566dd0029426a/2f6c8e69b2f6f5740525687b0065c710 )  
in the R5 Administration Help database. 
 
If you populate the "Deny messages from the following  
external Internet hosts to be sent to external Internet  
domains:", the MTA will allow mail from any domain not  
listed in that field. So it is better to leave that one  
blank.
  
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